Immunosuppressive non-myeloablative allografting as salvage therapy in advanced Hodgkin's disease.
نویسندگان
چکیده
منابع مشابه
Low intensity regimens with allogeneic hematopoietic stem cell transplantation as treatment of hematologic neoplasia.
Conventional myeloablative conditioning regimens for allografting rely on the use of toxic myeloablative and immunosuppressive therapies to achieve engraftment and control of hematologic neoplasias. Unfortunately, these regimens have resulted in substantial morbidity and mortality. Preclinical and pilot clinical studies have shown that conditioning regimens can be reduced in intensity (resultin...
متن کامل8.01.529 Hematopoietic Stem-Cell Transplantation for Non-Hodgkin Lymphomas
Non-Hodgkin Lymphoma (NHL) B-Cell aggressive subtype (except mantle cell) Myeloablative autologous, myeloablative allogeneic or reduced-intensity conditioning (RIC) allogeneic HSCT with curative intent may be considered medically necessary: As salvage for patients not in complete remission (CR) after first line chemotherapy induction; To achieve or consolidate a CR in chemotherapy sensitive...
متن کاملHodgkin\'s Disease
SUMMARY Hodgkin's disease has been known to medical practitioners for more than three centuries. The clinical and pathologic description of the disease published by Thomas. Hodgkin first in 183 2 when reported seven cases th-at he considered a new clinical entity. The incident, clinical feature, histologic, procedure of evaluation and staging of Hodgkin's disease are presented briefly. Part...
متن کاملSALVAGE CHEMO THERAPY WITH CYCLOPHOSPHAMIDE, DOXORUBICIN, AND CISPLATIN (CAP) IN ADVANCED BREAST CANCER
Twenty-one patients with advanced breast cancer (7 premenopausal and 14 postmenopausal women) were treated with a combination of cyclophosphamide, doxorubicin, and cisplatin (CAP). The median age of the patients was 43 years (range 36-61). This therapy was repeated every 3 weeks. Nine patients (group 1) received CAP as primary therapy for metastatic breast cancer, and twelve patients (group...
متن کاملCurrent treatment and immunotherapy of Hodgkin's lymphoma.
The treatment of Hodgkin's lymphoma has changed significantly over the last decades, rendering this entity one of the most curable human cancers. To date, about 80% of patients achieve long-term disease-free survival. Current strategies in first-line treatment aim at further improving outcome and thereby preventing therapy-induced complications, such as infertility, cardiopulmonary toxicity, an...
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ورودعنوان ژورنال:
- Haematologica
دوره 86 11 شماره
صفحات -
تاریخ انتشار 2001